Considerations To Know About ceesdekker
Considerations To Know About ceesdekker
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Nanotechnology gives A selection of prospects to add to biology. Here I will present examples in which nanofabrication – the chance to make confined constructions with dimensions at will – is utilised to look at the biophysics of solitary molecules and cells. I will current some examples from our lab:
Human Rad51 filaments on double- and single-stranded DNA: correlating standard and irregular sorts with recombination perform.
[Laughs] ‘It absolutely was definitely a great risk! At some time, I had been very well aware that it could go Completely wrong Which I could turn into a lot less productive, but I just ignored that. Curiosity has always been my strongest driving drive. And by chance all of it worked out.’
Deposition and atomic pressure microscopy of specific phthalocyanine polymers amongst nanofabricated electrodes
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever layout in 2005. (nl)
Our study ranges in the biophysics of DNA to synthetic cells and past. Make sure you have a look below at the spectrum of our current projects.
Length Charge of unique carbon nanotubes by nanostructuring While using the scanning tunneling microscope
Illustration (1) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is demonstrated in grey, the rim with the pore is highlighted in red, as well as a 3D rendering with the movement of the DNA rod is exhibited.
In 1993, as being a younger and keen affiliate professor at Delft University of Technological innovation, I'd initially centered the investigate efforts of my group on measuring the electrical conductance of an individual conducting-polymer molecule. Within just two years, we had established a device during which one wire of the phthalocyaninepolysiloxane polymer was related between two closely spaced steel nanoelectrodes.
Quite cool, but that wasn’t actually where by my curiosity lay. I planned to pioneer And that i had the feeling which was now not feasible, since the most appealing fundamental insights had previously been uncovered. But my field had produced quite a few exciting new resources to measure specific molecules. I made a decision which i planned to use this to biology, to have a look at it from the Bodily point of view.’
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2006, to start with demonstration of molecular sorting within a lab over a chip using biomotors; discovery of nanobubbles in sound-condition nanopores; and to start with estimate of electrokinetic Vitality conversion in a very nanofluidic channel
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes
It was an incredibly attention-grabbing time, in the course of which I gained a lot of help from Delft College https://www.ceesdekker.net of Technology, in which I used to be a professor at some time, and I began many collaborations with molecular biologists. That served me learn a whole lot.’